SGO1

Across TCGA patient cohorts, SGO1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,879 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SGO1-associated genes across cancer lineages are SLC40A1, SLC49A3, and CYP21A1P. Each is linked with SGO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGO1-to-partner and partner-to-SGO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGO1 versus SLC40A1 in BRCA, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGO1→partner) and Y-score (partner→SGO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC40A1 →	-1.829	-0.456	.003	.005	3	2
BRCA	SLC49A3 →	-1.751	-0.504	.001	.004	3	2
BRCA	CYP21A1P →	-1.738	-0.473	<.001	.003	3	2
BRCA	SLC4A8 →	-1.977	-0.742	<.001	<.001	3	2
LSCC	CYTH4 →	-0.963	-0.843	<.001	.007	3	1
LSCC	FOXRED2 →	+0.915	+0.833	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,879 associations by consensus.

SGO1 vs SLC40A1 — BRCA

Explore this scatter interactively →