SGO1

Across TCGA cell cohorts, SGO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,869 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SGO1-associated GO terms across cancer lineages are Mitotic spindle elongation, Negative regulation of mitotic nuclear division, and Spindle elongation. Each is linked with SGO1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SGO1-to-partner and partner-to-SGO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by SGO1-low versus SGO1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGO1→partner) and Y-score (partner→SGO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Mitotic spindle elongation →	+0.322	+1.362	<.001	<.001	3	20
SKIN	Negative regulation of mitotic nuclear division →	+0.179	+1.092	<.001	<.001	3	20
KIDNEY	Spindle elongation →	+0.364	+1.409	<.001	<.001	3	20
KIDNEY	Mitotic spindle midzone assembly →	+0.322	+1.362	<.001	<.001	3	20
OESOPHAGUS	Regulation of nuclear division →	+0.129	+1.053	<.001	<.001	3	20
OESOPHAGUS	Negative regulation of nuclear division →	+0.185	+1.267	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,869 associations by consensus.

Mitotic spindle elongation by SGO1 expression — KIDNEY

Explore this box plot interactively →