SGO1-AS1

Across TCGA pan-cancer cohorts, SGO1-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated SGO1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SGO1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SGO1-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and GBM show a favorable association.

KIRC, CESC, and GBM are the cancer types where SGO1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.487	0.677	<.001	93	view →
CESC	DFS	Tertile	All	0.917	0.775	<.001	78	view →
GBM	DFS	Tertile	All	0.284	0.164	.002	28	view →
MESO	DFS	Tertile	All	0.172	0.531	.010	27	view →
THCA	DFS	Tertile	IV	0.509	0.899	.016	18	view →
LIHC	OS	Tertile	All	0.297	0.570	<.001	16	view →
UVM	DFS	Tertile	III,IV	0.071	0.636	<.001	9	view →
SKCM	DFS	Quartile	IV	0.040	0.591	.008	8	view →
THYM	DFS	Quartile	All	0.527	0.880	.012	7	view →
OV	DFS	Tertile	III,IV	0.591	0.501	.039	6	view →
READ	OS	Tertile	III,IV	0.400	0.747	.045	6	view →
BLCA	OS	Median	IV	0.697	0.503	.011	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

SGO1-AS1–KIRC (OS)

Open the KIRC breakdown →