SGMS2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SGMS2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,358 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SGMS2-associated genes across cancer lineages are GNA14, FBP1, and TLR5. Each is linked with SGMS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGMS2-to-partner and partner-to-SGMS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGMS2 versus GNA14 in LUAD, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGMS2→partner) and Y-score (partner→SGMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADGNA14 →+0.882+0.436.002<.00132
OVFBP1 →+1.428+1.070.002<.00132
OVTLR5 →+0.971+0.914.004.00632
OVZFP2 →+0.508+0.757.008.00332
OVRPL23AP48 →-0.862-1.197.001<.00132
OVLINC01797 →+1.370+0.810.007.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,358 associations by consensus.

SGMS2 vs GNA14 — LUAD

Per-sample scatter of SGMS2 vs GNA14 in LUAD (Pearson r = 0.37).

Explore this scatter interactively →

Exploration