SGMS2

Across TCGA cell cohorts, SGMS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,630 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SGMS2-associated GO terms across cancer lineages are Cellular response to environmental stimulus, Cellular response to abiotic stimulus, and Skeletal myofibril assembly. Each is linked with SGMS2 in more than 14 cancer types. Because this analysis shows association rather than direction, both SGMS2-to-partner and partner-to-SGMS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to environmental stimulus grouped by SGMS2-low versus SGMS2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGMS2→partner) and Y-score (partner→SGMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cellular response to environmental stimulus →	+0.056	+1.571	.008	.009	3	15
LUNG_NSCLC_LUSC	Cellular response to abiotic stimulus →	+0.056	+1.571	.008	.009	3	15
BLOOD_Leukemia	Skeletal myofibril assembly →	+0.482	+0.568	.002	<.001	3	13
BONE	Positive regulation of plasma membrane repair →	+0.306	+2.540	<.001	<.001	3	13
BONE	Regulation of chemotaxis →	+0.108	+2.755	<.001	<.001	3	13
BONE	Regulation of plasma membrane repair →	+0.354	+2.577	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,630 associations by consensus.

Cellular response to environmental stimulus by SGMS2 expression — LUNG_NSCLC_LUSC

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