Across TCGA patient cohorts, SGMS1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,217 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SGMS1-associated genes across cancer lineages are EHF, FAM83A, and NIPAL2. Each is linked with SGMS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SGMS1-to-partner and partner-to-SGMS1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGMS1→partner) and Y-score (partner→SGMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EHF →	+1.356	+0.587	<.001	<.001	3	3
LSCC	FAM83A →	+1.868	+0.447	<.001	<.001	3	3
OV	NIPAL2 →	+1.048	+0.636	<.001	<.001	3	2
OV	C17orf75 →	-0.501	-0.642	<.001	<.001	3	2
HNSC	PPIAP26 →	+1.392	+0.497	<.001	<.001	3	2
OV	RCOR2 →	-1.323	-0.694	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,217 associations by consensus.

Exploration

SGMS1 survival (RNA) · tumor vs normal (RNA) · all SGMS1 data types