Across TCGA patient cohorts, SGMS1 mutation is significantly associated with the RNA expression of many other genes, with 4,661 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SGMS1-associated genes across cancer lineages are LINC02304, BPY2DP, and XAGE1B. Each is linked with SGMS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SGMS1-to-partner and partner-to-SGMS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGMS1→partner) and Y-score (partner→SGMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02304 →	+0.021	+2.670	<.001	.002	3	3
LUSC	BPY2DP →	+0.147	+5.548	.006	.004	3	3
BLCA	XAGE1B →	+0.229	+4.680	<.001	.003	3	2
HNSC	RNU6-1078P →	+0.278	+7.954	<.001	.008	3	2
SKCM	BCL2L2-PABPN1 →	+0.302	+1.587	<.001	.002	3	2
SKCM	RPAP1 →	+0.405	+1.549	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,661 associations by consensus.

Exploration

SGMS1 survival (RNA) · tumor vs normal (RNA) · all SGMS1 data types