Across TCGA cell cohorts, SGMS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,601 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SGMS1-associated GO terms across cancer lineages are Regulation of glucosylceramide biosynthetic process, Sphingomyelin metabolic process, and Sphingomyelin biosynthetic process. Each is linked with SGMS1 in more than 18 cancer types. Because this analysis shows association rather than direction, both SGMS1-to-partner and partner-to-SGMS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGMS1→partner) and Y-score (partner→SGMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of glucosylceramide biosynthetic process →	+0.243	+1.482	<.001	<.001	3	19
LUNG_SCLC	Sphingomyelin metabolic process →	+0.109	+0.963	<.001	<.001	3	15
STOMACH	Sphingomyelin biosynthetic process →	+0.174	+0.965	<.001	<.001	3	14
BONE	Regulation of cell-matrix adhesion →	+0.137	+1.124	<.001	<.001	3	11
OESOPHAGUS	Regulation of hippo signaling →	+0.097	+0.843	.004	.005	2	12
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.065	+1.163	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,601 associations by consensus.

Exploration

SGMS1 survival (RNA) · tumor vs normal (RNA) · all SGMS1 data types