Across TCGA cell cohorts, SGMS1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SGMS1-associated genes across cancer lineages are RBMY1J, ADRA1A, and APOL5. Each is linked with SGMS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGMS1-to-partner and partner-to-SGMS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGMS1→partner) and Y-score (partner→SGMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RBMY1J →	+0.006	+4.022	<.001	.006	3	2
BLOOD_Leukemia	ADRA1A →	+0.192	+3.705	<.001	.007	3	1
BLOOD_Leukemia	APOL5 →	+0.012	+4.060	.002	.003	3	1
BLOOD_Leukemia	MORN5 →	+0.282	+3.855	<.001	.007	3	1
BLOOD_Leukemia	GUCA2A →	+0.031	+4.384	<.001	.006	3	1
BLOOD_Leukemia	DEFB134 →	+0.013	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

SGMS1 survival (RNA) · tumor vs normal (RNA) · all SGMS1 data types