Across TCGA pan-cancer cohorts, SGMS1-AS1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SGMS1-AS1 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SGMS1-AS1 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated SGMS1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, UCS, and SKCM are the cancer types where SGMS1-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.625	.007	32	view →
UCS	OS	Median	III,IV	0.104	0.591	.004	24	view →
SKCM	DFS	Median	II,III,IV	0.891	0.559	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SGMS1-AS1 tumor-vs-normal RNA expression · all SGMS1-AS1 data types