Across TCGA patient cohorts, SGMS1-AS1 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SGMS1-AS1-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and FoxM1. Each is linked with SGMS1-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGMS1-AS1-to-partner and partner-to-SGMS1-AS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGMS1-AS1→partner) and Y-score (partner→SGMS1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.204	-2.459	.023	.018	3	1
UCEC	A-Raf_pS299 →	-0.113	-2.459	.008	.018	3	1
UCEC	FoxM1 →	+0.190	+1.584	.042	.019	3	1
UCEC	JNK2 →	+0.215	+3.611	.002	.001	3	1
UCEC	Ku80 →	+0.263	+2.425	.001	.001	3	1
UCEC	MEK1 →	+0.373	+2.321	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

SGMS1-AS1 survival (RNA) · tumor vs normal (RNA) · all SGMS1-AS1 data types