SGK3

Across TCGA patient cohorts, SGK3 mutation is significantly associated with the RNA expression of many other genes, with 1,487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SGK3-associated genes across cancer lineages are OR4K13, RFKP1, and LINC01941. Each is linked with SGK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGK3-to-partner and partner-to-SGK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4K13 grouped by SGK3-low versus SGK3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGK3→partner) and Y-score (partner→SGK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR4K13 →	+0.029	+5.040	<.001	.002	3	2
UCEC	RFKP1 →	+0.065	+2.104	.005	.008	3	2
UCEC	LINC01941 →	+0.021	+3.245	.001	.003	3	2
BRCA	RNU6-1252P →	+0.291	+7.731	<.001	.009	3	2
SKCM	RNA5SP68 →	+0.454	+4.867	<.001	.005	3	2
COAD	OR6U2P →	+0.117	+5.824	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,487 associations by consensus.

OR4K13 by SGK3 expression — BLCA

Explore this box plot interactively →