SGK3

Across TCGA cell cohorts, SGK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,958 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SGK3-associated GO terms across cancer lineages are Lysosomal transport, Endosome to lysosome transport, and Vacuolar transport. Each is linked with SGK3 in more than 8 cancer types. Because this analysis shows association rather than direction, both SGK3-to-partner and partner-to-SGK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal transport grouped by SGK3-low versus SGK3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGK3→partner) and Y-score (partner→SGK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Lysosomal transport →	+0.048	+0.670	.003	.005	3	9
KIDNEY	Endosome to lysosome transport →	+0.067	+0.809	<.001	<.001	3	9
LIVER	Vacuolar transport →	+0.060	+1.278	.003	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of centrosome duplication →	+0.074	+0.868	<.001	<.001	3	8
BREAST	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.063	+1.337	<.001	<.001	3	8
SOFT_TISSUE	Endosomal lumen acidification →	+0.087	+0.691	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,958 associations by consensus.

Lysosomal transport by SGK3 expression — LIVER

Explore this box plot interactively →