SGK2

Across TCGA patient cohorts, SGK2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,853 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SGK2-associated genes across cancer lineages are LRRC31, FMNL3, and DCLK2. Each is linked with SGK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SGK2-to-partner and partner-to-SGK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGK2 versus LRRC31 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGK2→partner) and Y-score (partner→SGK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRRC31 →	+2.054	+0.919	<.001	<.001	3	3
UCEC	FMNL3 →	-0.919	-1.019	.001	<.001	3	3
UCEC	DCLK2 →	-0.775	-0.870	.001	<.001	3	3
UCEC	LINC02038 →	+1.378	+0.779	.001	.002	3	3
UCEC	EGFL8 →	-0.901	-0.775	<.001	.006	3	3
UCEC	ZNF532 →	-0.845	-1.075	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,853 associations by consensus.

SGK2 vs LRRC31 — UCEC

Explore this scatter interactively →