SGCG

Across TCGA patient cohorts, SGCG RNA expression is significantly associated with the protein abundance of many other proteins, with 18,408 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SGCG-associated proteins across cancer lineages are ADIPOQ, HDGFL3, and PALM. Each is linked with SGCG in more than 5 cancer types. Because this analysis shows association rather than direction, both SGCG-to-partner and partner-to-SGCG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGCG versus ADIPOQ in BRCA, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGCG→partner) and Y-score (partner→SGCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADIPOQ →	+0.586	+1.102	<.001	.001	3	5
GBM	HDGFL3 →	+0.685	+0.804	<.001	<.001	3	5
BRCA	PALM →	+0.853	+0.956	<.001	<.001	3	5
LUAD	PGAM1_S31 →	-0.529	-0.523	<.001	<.001	3	5
BRCA	SORBS1 →	+0.894	+1.099	<.001	<.001	3	5
BRCA	KANK2 →	+0.599	+0.907	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,408 associations by consensus.

SGCG vs ADIPOQ — BRCA

Explore this scatter interactively →