SGCG

Across TCGA cell cohorts, SGCG RNA expression is significantly associated with the go_rna of many other GO terms, with 1,248 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SGCG-associated GO terms across cancer lineages are Positive regulation of DNA repair, Translational initiation, and Regulation of protein localization to Cajal body. Each is linked with SGCG in more than 8 cancer types. Because this analysis shows association rather than direction, both SGCG-to-partner and partner-to-SGCG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by SGCG-low versus SGCG-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGCG→partner) and Y-score (partner→SGCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of DNA repair →	+0.038	+0.261	<.001	.007	3	8
UPPER_AERODIGESTIVE_TRACT	Translational initiation →	+0.084	+0.162	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to Cajal body →	+0.067	+0.161	.002	.007	2	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to Cajal body →	+0.067	+0.161	.002	.007	2	9
LARGE_INTESTINE	Lipoprotein transport →	+0.098	+0.047	<.001	.008	3	7
LARGE_INTESTINE	Calcium-independent cell-matrix adhesion →	+0.173	+0.045	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,248 associations by consensus.

Positive regulation of DNA repair by SGCG expression — LUNG_NSCLC_LUAD

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