SGCG

Across TCGA cell cohorts, SGCG mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SGCG-associated genes across cancer lineages are TEX43 and CD300H. Each is linked with SGCG in more than 1 cancer types. Because this analysis shows association rather than direction, both SGCG-to-partner and partner-to-SGCG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX43 grouped by SGCG-low versus SGCG-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGCG→partner) and Y-score (partner→SGCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TEX43 →	+0.141	+5.969	<.001	.001	3	1
LARGE_INTESTINE	CD300H →	+0.045	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TEX43 by SGCG expression — BLOOD_Leukemia

Explore this box plot interactively →