SFXN5

Across TCGA patient cohorts, SFXN5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,374 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SFXN5-associated proteins across cancer lineages are UBE2J1, MSH2, and MSH6. Each is linked with SFXN5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SFXN5-to-partner and partner-to-SFXN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFXN5 versus UBE2J1 in LSCC, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN5→partner) and Y-score (partner→SFXN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBE2J1 →	-0.581	-0.532	<.001	<.001	3	4
LSCC	MSH2 →	+0.315	+0.361	.002	<.001	3	4
LSCC	MSH6 →	+0.605	+0.426	<.001	<.001	3	4
CCRCC	CTH →	-0.440	-0.452	<.001	<.001	3	4
GBM	YKT6 →	+0.219	+0.350	<.001	.004	3	3
PDAC	ORC2_T226 →	+0.981	+0.503	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,374 associations by consensus.

SFXN5 vs UBE2J1 — LSCC

Explore this scatter interactively →