SFXN5

Across TCGA patient cohorts, SFXN5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,829 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SFXN5-associated genes across cancer lineages are MB, OTX1, and SNORD46. Each is linked with SFXN5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SFXN5-to-partner and partner-to-SFXN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFXN5 versus MB in OV, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN5→partner) and Y-score (partner→SFXN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MB →	+0.869	+0.359	.006	.008	3	3
BRCA	OTX1 →	-0.796	-0.458	<.001	<.001	3	3
HNSC	SNORD46 →	-0.956	-0.246	.004	<.001	3	3
BRCA	SFT2D2 →	-0.908	-0.559	<.001	<.001	3	3
BRCA	DTNB-AS1 →	-0.893	-0.689	<.001	<.001	3	3
HNSC	PARD6BP1 →	-0.642	-0.226	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,829 associations by consensus.

SFXN5 vs MB — OV

Explore this scatter interactively →