SFXN5

Across TCGA patient cohorts, SFXN5 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,861 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SFXN5-associated proteins across cancer lineages are ALDH5A1, ATP5PB, and HADHA. Each is linked with SFXN5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SFXN5-to-partner and partner-to-SFXN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFXN5 versus ALDH5A1 in GBM, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN5→partner) and Y-score (partner→SFXN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ALDH5A1 →	+0.540	+0.392	<.001	<.001	3	6
PDAC	ATP5PB →	+0.627	+0.472	<.001	<.001	3	5
GBM	HADHA →	+0.287	+0.466	<.001	<.001	3	5
UCEC	IMMT →	+0.389	+0.439	<.001	<.001	3	5
COAD	HSD17B4 →	+0.434	+0.639	.002	<.001	3	5
GBM	ITPR2 →	+0.330	+0.475	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,861 associations by consensus.

SFXN5 vs ALDH5A1 — GBM

Explore this scatter interactively →