SFXN5

Across TCGA cell cohorts, SFXN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,010 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SFXN5-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Negative regulation of calcium ion export across plasma membrane, and Spindle organization. Each is linked with SFXN5 in more than 14 cancer types. Because this analysis shows association rather than direction, both SFXN5-to-partner and partner-to-SFXN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by SFXN5-low versus SFXN5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN5→partner) and Y-score (partner→SFXN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of cell cycle process →	+0.078	+1.085	<.001	<.001	3	15
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.083	+0.964	.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Spindle organization →	+0.081	+1.175	.002	<.001	3	14
OESOPHAGUS	Regulation of DNA-templated DNA replication →	+0.114	+1.070	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of cell cycle phase transition →	+0.082	+1.131	<.001	<.001	3	13
OESOPHAGUS	Negative regulation of chromosome organization →	+0.108	+1.078	.004	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,010 associations by consensus.

Negative regulation of cell cycle process by SFXN5 expression — OESOPHAGUS

Explore this box plot interactively →