SFXN3

Across TCGA patient cohorts, SFXN3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,577 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFXN3-associated genes across cancer lineages are ZCCHC24, TIMP3, and ZEB1. Each is linked with SFXN3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SFXN3-to-partner and partner-to-SFXN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFXN3 versus ZCCHC24 in COAD, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN3→partner) and Y-score (partner→SFXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZCCHC24 →	+0.751	+0.274	<.001	<.001	3	8
BRCA	TIMP3 →	+1.373	+0.427	<.001	<.001	3	7
COAD	ZEB1 →	+1.120	+0.389	<.001	<.001	3	7
COAD	EPDR1 →	+0.978	+0.374	.001	<.001	3	6
BRCA	SYDE1 →	+0.819	+0.436	<.001	<.001	3	6
BRCA	MEIS3 →	+1.395	+0.456	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,577 associations by consensus.

SFXN3 vs ZCCHC24 — COAD

Explore this scatter interactively →