SFXN3

Across TCGA cell cohorts, SFXN3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,517 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SFXN3-associated genes across cancer lineages are HOXA3, ADAMTS14, and AKAP3. Each is linked with SFXN3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SFXN3-to-partner and partner-to-SFXN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFXN3 versus HOXA3 in LUNG_SCLC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN3→partner) and Y-score (partner→SFXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	HOXA3 →	+2.973	+0.888	.001	.001	3	3
LARGE_INTESTINE	ADAMTS14 →	+1.307	+1.685	.001	.002	3	3
BLOOD_Lymphoma	AKAP3 →	-0.399	-1.076	.001	.003	3	2
BLOOD_Lymphoma	MAPK14 →	+1.130	+1.291	.006	.002	2	3
BLOOD_Lymphoma	CDYL2 →	+1.690	+1.237	<.001	<.001	3	2
BLOOD_Lymphoma	RIN1 →	-0.578	-1.213	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,517 associations by consensus.

SFXN3 vs HOXA3 — LUNG_SCLC

Explore this scatter interactively →