SFXN2

Across TCGA patient cohorts, SFXN2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,734 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SFXN2-associated genes across cancer lineages are SNAI2, NCS1, and CORO1C. Each is linked with SFXN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SFXN2-to-partner and partner-to-SFXN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFXN2 versus SNAI2 in OV, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN2→partner) and Y-score (partner→SFXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SNAI2 →	-1.308	-0.489	<.001	<.001	3	6
UCEC	NCS1 →	-0.996	-0.586	.001	.006	3	5
UCEC	CORO1C →	-0.468	-0.588	.002	<.001	3	5
OV	LOX →	-1.514	-0.519	<.001	<.001	3	5
OV	ADAMTS5 →	-0.981	-0.502	<.001	<.001	3	5
COAD	DNAJB4 →	-0.577	-0.284	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,734 associations by consensus.

SFXN2 vs SNAI2 — OV

Explore this scatter interactively →