SFXN2

Across TCGA cell cohorts, SFXN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,491 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SFXN2-associated GO terms across cancer lineages are Spindle elongation, Mitochondrial transmembrane transport, and DNA-templated DNA replication. Each is linked with SFXN2 in more than 15 cancer types. Because this analysis shows association rather than direction, both SFXN2-to-partner and partner-to-SFXN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by SFXN2-low versus SFXN2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN2→partner) and Y-score (partner→SFXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Spindle elongation →	+0.235	+1.265	<.001	<.001	3	16
BONE	Mitochondrial transmembrane transport →	+0.129	+1.525	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.111	+1.344	.001	<.001	3	15
SOFT_TISSUE	Spindle midzone assembly →	+0.244	+1.579	<.001	<.001	3	15
BREAST	Mitochondrial transport →	+0.111	+1.865	<.001	<.001	3	15
BONE	Mitochondrial DNA repair →	+0.156	+1.568	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,491 associations by consensus.

Spindle elongation by SFXN2 expression — SOFT_TISSUE

Explore this box plot interactively →