SFXN1

Across TCGA patient cohorts, SFXN1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,103 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFXN1-associated genes across cancer lineages are GYPC, COL14A1, and LMAN2. Each is linked with SFXN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SFXN1-to-partner and partner-to-SFXN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFXN1 versus GYPC in BRCA, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN1→partner) and Y-score (partner→SFXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GYPC →	-0.715	-0.287	<.001	.004	3	7
CCRCC	COL14A1 →	-1.205	-0.244	<.001	.005	3	6
HNSC	LMAN2 →	+0.657	+0.242	.006	.001	2	6
OV	NHP2 →	+0.601	+0.374	<.001	.006	3	5
OV	TMED9 →	+0.470	+0.316	.001	.002	3	5
OV	MAPK9 →	+0.492	+0.325	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,103 associations by consensus.

SFXN1 vs GYPC — BRCA

Explore this scatter interactively →