SFTPD

Across TCGA patient cohorts, SFTPD protein abundance is significantly associated with the RNA expression of many other genes, with 9,312 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFTPD-associated genes across cancer lineages are LGALS2, CTSG, and CDKN3. Each is linked with SFTPD in more than 2 cancer types. Because this analysis shows association rather than direction, both SFTPD-to-partner and partner-to-SFTPD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFTPD versus LGALS2 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPD→partner) and Y-score (partner→SFTPD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LGALS2 →	+0.630	+0.552	<.001	<.001	3	2
LUAD	CTSG →	+1.025	+1.024	<.001	<.001	3	2
LUAD	CDKN3 →	-0.864	-0.835	.002	.001	3	2
LUAD	GINS1 →	-0.982	-0.954	<.001	<.001	3	2
LUAD	MYBL2 →	-1.277	-0.730	<.001	.005	3	2
HNSC	E2F1 →	-1.301	-0.410	.002	.009	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,312 associations by consensus.

SFTPD vs LGALS2 — LSCC

Explore this scatter interactively →