SFTPD

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SFTPD RNA expression is significantly associated with the go_rna of many other GO terms, with 2,137 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SFTPD-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Vesicle budding from membrane, and Proteasomal ubiquitin-independent protein catabolic process. Each is linked with SFTPD in more than 7 cancer types. Because this analysis shows association rather than direction, both SFTPD-to-partner and partner-to-SFTPD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SFTPD-low versus SFTPD-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPD→partner) and Y-score (partner→SFTPD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNegative regulation of myoblast fusion →+0.137+0.313<.001.00538
LUNG_NSCLC_LUADVesicle budding from membrane →+0.061+0.838<.001<.00137
KIDNEYProteasomal ubiquitin-independent protein catabolic process →+0.072+0.194<.001<.00137
STOMACHNegative regulation of syncytium formation by plasma membrane fusion →+0.136+0.312<.001.00428
OESOPHAGUSB cell proliferation involved in immune response →-0.149-0.412.006.00137
PANCREASAdenylate cyclase-modulating G protein-coupled receptor signaling pathway →-0.075-0.342<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,137 associations by consensus.

Negative regulation of myoblast fusion by SFTPD expression — STOMACH

Box plot of Negative regulation of myoblast fusion in SFTPD-low vs SFTPD-high samples in STOMACH.

Explore this box plot interactively →

Exploration