SFTPD-AS1

Across TCGA pan-cancer cohorts, SFTPD-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated SFTPD-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher SFTPD-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SFTPD-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and UCEC show a favorable association.

UCS, UCEC, and LUSC are the cancer types where SFTPD-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.558	0.188	.005	46	view →
UCEC	DFS	Median	III,IV	0.882	0.721	.003	42	view →
LUSC	OS	Quartile	All	0.552	0.736	.001	36	view →
PAAD	OS	Quartile	All	0.374	0.683	<.001	28	view →
ESCA	OS	Quartile	III,IV	0.670	0.315	.013	21	view →
LGG	OS	Tertile	All	0.943	0.832	<.001	19	view →
BLCA	OS	Median	IV	0.249	0.570	.022	15	view →
SARC	DFS	Quartile	All	0.746	0.517	.009	13	view →
TGCT	DFS	Tertile	All	0.711	0.919	.011	10	view →
THYM	DFS	Median	III,IV	1.000	0.546	.029	9	view →
LIHC	OS	Quartile	All	0.975	0.731	.009	9	view →
LUAD	OS	Tertile	All	0.851	0.700	.011	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

SFTPD-AS1–UCS (DFS)

Open the UCS breakdown →