SFTPC

Across TCGA patient cohorts, SFTPC RNA expression is significantly associated with the protein abundance of many other proteins, with 15,153 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFTPC-associated proteins across cancer lineages are TNS2_S648, RPS6KA2, and PHACTR1. Each is linked with SFTPC in more than 2 cancer types. Because this analysis shows association rather than direction, both SFTPC-to-partner and partner-to-SFTPC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFTPC versus TNS2_S648 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPC→partner) and Y-score (partner→SFTPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TNS2_S648 →	+0.579	+3.121	<.001	<.001	3	3
GBM	RPS6KA2 →	+0.908	+0.529	<.001	<.001	3	3
GBM	PHACTR1 →	+0.909	+1.075	<.001	<.001	3	3
GBM	PHACTR1_S237 →	+0.776	+0.533	<.001	<.001	3	3
GBM	ARHGAP44 →	+1.094	+0.919	<.001	<.001	3	3
GBM	PPP1R12B →	+0.391	+0.928	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,153 associations by consensus.

SFTPC vs TNS2_S648 — LSCC

Explore this scatter interactively →