SFTPC

Across TCGA cell cohorts, SFTPC RNA expression is significantly associated with the go_rna of many other GO terms, with 1,787 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SFTPC-associated GO terms across cancer lineages are ATP metabolic process, Regulation of autophagosome assembly, and Cellular respiration. Each is linked with SFTPC in more than 4 cancer types. Because this analysis shows association rather than direction, both SFTPC-to-partner and partner-to-SFTPC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP metabolic process grouped by SFTPC-low versus SFTPC-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPC→partner) and Y-score (partner→SFTPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ATP metabolic process →	+0.046	+0.898	.001	.001	3	5
PANCREAS	Regulation of autophagosome assembly →	+0.056	+0.100	<.001	.005	3	4
SKIN	Cellular respiration →	+0.077	+1.451	<.001	<.001	3	4
SKIN	Aerobic respiration →	+0.090	+1.792	<.001	<.001	3	4
SKIN	Purine ribonucleoside triphosphate metabolic process →	+0.043	+0.886	.001	.001	3	4
SKIN	Negative regulation of hydrogen peroxide metabolic process →	+0.183	+1.877	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,787 associations by consensus.

ATP metabolic process by SFTPC expression — SKIN

Explore this box plot interactively →