SFTPB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SFTPB protein abundance is significantly associated with the RNA expression of many other genes, with 7,161 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFTPB-associated genes across cancer lineages are STK32A-AS1, CENPM, and MCM5. Each is linked with SFTPB in more than 1 cancer types. Because this analysis shows association rather than direction, both SFTPB-to-partner and partner-to-SFTPB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFTPB versus STK32A-AS1 in UCEC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPB→partner) and Y-score (partner→SFTPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSTK32A-AS1 →+0.765+1.922.009.00632
LUADCENPM →-0.734-0.574<.001<.00132
LUADMCM5 →-0.465-0.740<.001<.00132
LUADPOLE2 →-0.688-0.525<.001<.00132
LSCCCDKN3 →-1.038-0.693<.001<.00132
LUADMTHFD1 →-0.515-0.968<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

SFTPB vs STK32A-AS1 — UCEC

Per-sample scatter of SFTPB vs STK32A-AS1 in UCEC (Pearson r = 0.75).

Explore this scatter interactively →

Exploration