SFTPB

Across TCGA cell cohorts, SFTPB RNA expression is significantly associated with the go_rna of many other GO terms, with 1,014 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SFTPB-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of centrosome cycle, and Glycerophospholipid metabolic process. Each is linked with SFTPB in more than 6 cancer types. Because this analysis shows association rather than direction, both SFTPB-to-partner and partner-to-SFTPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SFTPB-low versus SFTPB-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPB→partner) and Y-score (partner→SFTPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.053	+0.055	.001	.009	2	7
BLOOD_Leukemia	Regulation of centrosome cycle →	+0.038	+0.059	<.001	.006	3	5
BLOOD_Leukemia	Glycerophospholipid metabolic process →	+0.024	+0.101	<.001	.003	3	4
BONE	Disruption of cell in another organism →	-0.139	-0.108	.009	.009	3	4
BONE	Killing of cells of another organism →	-0.139	-0.108	.009	.009	3	4
SOFT_TISSUE	Negative regulation of fibroblast proliferation →	+0.053	+0.068	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,014 associations by consensus.

Negative regulation of myoblast fusion by SFTPB expression — BLOOD_Leukemia

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