Across TCGA pan-cancer cohorts, SFTPA3P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SFTPA3P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SFTPA3P RNA is repressed in tumor relative to normal tissue. In most cancer types SFTPA3P is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

LUSC, BRCA, and LUAD are the cancer types where SFTPA3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SFTPA3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.236	<.001	7	view →
BRCA	All	All	−0.025	.022	4	view →
LUAD	All	All	−0.099	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SFTPA3P RNA expression & survival · all SFTPA3P data types