Across TCGA patient cohorts, SFTPA2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,095 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFTPA2-associated genes across cancer lineages are HMOX2, CSF3R, and SFTPA1. Each is linked with SFTPA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFTPA2-to-partner and partner-to-SFTPA2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPA2→partner) and Y-score (partner→SFTPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HMOX2 →	-0.496	-0.568	<.001	<.001	3	2
LSCC	CSF3R →	+1.015	+0.524	<.001	<.001	3	2
LSCC	SFTPA1 →	+2.869	+0.500	<.001	<.001	3	2
LSCC	ADGRE3 →	+0.562	+0.323	<.001	<.001	3	2
LSCC	NRGN →	+0.981	+0.439	<.001	<.001	3	2
LUAD	AMFR →	-0.357	-0.505	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,095 associations by consensus.

Exploration

SFTPA2 survival (RNA) · tumor vs normal (RNA) · all SFTPA2 data types