Across TCGA patient cohorts, SFTPA2 mutation is significantly associated with the RNA expression of many other genes, with 453 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SFTPA2-associated genes across cancer lineages are CTU2, PVR, and ACD. Each is linked with SFTPA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFTPA2-to-partner and partner-to-SFTPA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPA2→partner) and Y-score (partner→SFTPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CTU2 →	+0.433	+3.346	.007	.005	3	2
UCEC	PVR →	+0.643	+3.338	.001	.005	3	2
UCEC	ACD →	+0.648	+3.732	<.001	<.001	3	2
SKCM	MAP7D1 →	+0.611	+3.245	<.001	.008	3	2
SKCM	POLA2 →	+0.510	+3.465	.006	.003	3	2
SKCM	METTL22 →	+0.512	+3.350	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 453 associations by consensus.

Exploration

SFTPA2 survival (RNA) · tumor vs normal (RNA) · all SFTPA2 data types