Across TCGA patient cohorts, SFTPA2 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SFTPA2-associated genes across cancer lineages are NKT, naive B-cells, and aDC. Each is linked with SFTPA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFTPA2-to-partner and partner-to-SFTPA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPA2→partner) and Y-score (partner→SFTPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NKT →	-0.108	-3.159	.029	.019	3	2
LIHC	naive B-cells →	+0.031	+3.237	<.001	.047	3	1
SKCM	aDC →	-0.129	-3.453	.007	.005	3	1
SKCM	Neurons →	+0.022	+2.341	.019	.020	3	1
UCEC	DC →	+0.041	+3.764	<.001	<.001	3	1
UCEC	Memory B-cells →	+0.031	+3.797	.014	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

SFTPA2 survival (RNA) · tumor vs normal (RNA) · all SFTPA2 data types