Across TCGA cell cohorts, SFTPA2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SFTPA2-associated genes across cancer lineages are COX6A2, TBC1D21, and OR52H1. Each is linked with SFTPA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFTPA2-to-partner and partner-to-SFTPA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPA2→partner) and Y-score (partner→SFTPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	COX6A2 →	+0.082	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR52H1 →	+0.031	+4.347	<.001	.001	3	1
LARGE_INTESTINE	CCER1 →	+0.013	+4.562	<.001	<.001	3	1
SKIN	OR7A10 →	+0.023	+6.022	<.001	.001	3	1
SKIN	CYLC1 →	+0.013	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

SFTPA2 survival (RNA) · tumor vs normal (RNA) · all SFTPA2 data types