Across TCGA cell cohorts, SFTA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,770 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SFTA3-associated GO terms across cancer lineages are Globus pallidus development, Spliceosomal tri-snRNP complex assembly, and Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11). Each is linked with SFTA3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SFTA3-to-partner and partner-to-SFTA3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTA3→partner) and Y-score (partner→SFTA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Globus pallidus development →	+2.265	+4.611	<.001	<.001	3	7
OESOPHAGUS	Spliceosomal tri-snRNP complex assembly →	+0.112	+0.302	.001	.003	3	6
LUNG_NSCLC_LUAD	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.080	+3.128	<.001	<.001	3	5
OESOPHAGUS	Negative regulation of post-translational protein modification →	+0.091	+0.345	.003	.008	3	5
OESOPHAGUS	Negative regulation of protein modification by small protein conjugation or removal →	+0.091	+0.206	.008	.007	3	5
LUNG_SCLC	mRNA destabilization →	+0.036	+2.873	.005	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,770 associations by consensus.

Exploration

SFTA3 survival (RNA) · tumor vs normal (RNA) · all SFTA3 data types