Across TCGA pan-cancer cohorts, SFTA2 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SFTA2’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where SFTA2 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SFTA2 is over-expressed in tumor.

PDAC and LUAD are the cancer types where SFTA2 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SFTA2 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PDAC	All	All	+1.049	.004	4	view →
LUAD	Female	All	+0.625	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SFTA2 RNA expression & survival · all SFTA2 data types