SFT2D3

Across TCGA patient cohorts, SFT2D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 231 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible SFT2D3-associated GO terms across cancer lineages are Positive regulation of myeloid leukocyte cytokine production involved in immune response, Pyrimidine nucleoside metabolic process, and Arginine metabolic process. Each is linked with SFT2D3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFT2D3-to-partner and partner-to-SFT2D3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of myeloid leukocyte cytokine production involved in immune response grouped by SFT2D3-low versus SFT2D3-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFT2D3→partner) and Y-score (partner→SFT2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of myeloid leukocyte cytokine production involved in immune response →	-0.083	-0.332	.001	.002	3	1
SCLC	Pyrimidine nucleoside metabolic process →	-0.132	-0.482	.001	<.001	3	1
SCLC	Arginine metabolic process →	-0.140	-0.468	<.001	<.001	3	1
SCLC	Tyrosine metabolic process →	-0.123	-0.375	.002	<.001	3	1
SCLC	Microtubule nucleation →	+0.072	+0.395	.002	<.001	3	1
SCLC	Positive regulation of leukocyte proliferation →	-0.082	-0.330	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 231 associations by consensus.

Positive regulation of myeloid leukocyte cytokine production involved in immune response by SFT2D3 expression — SCLC

Explore this box plot interactively →