Across TCGA patient cohorts, SFT2D2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,960 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SFT2D2-associated genes across cancer lineages are EEF1AKNMT, RAB11FIP4, and ARRB1. Each is linked with SFT2D2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SFT2D2-to-partner and partner-to-SFT2D2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFT2D2→partner) and Y-score (partner→SFT2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EEF1AKNMT →	+0.448	+0.302	.001	.009	3	4
GBM	RAB11FIP4 →	+0.822	+0.304	<.001	<.001	3	3
GBM	ARRB1 →	+0.551	+0.292	<.001	<.001	3	3
GBM	HSPG2 →	-0.620	-0.213	<.001	.006	3	3
LUAD	ALAD →	+0.514	+0.543	<.001	<.001	3	3
GBM	PDK1 →	-0.578	-0.276	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,960 associations by consensus.

Exploration

SFT2D2 survival (RNA) · tumor vs normal (RNA) · all SFT2D2 data types