SFT2D2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SFT2D2 mutation is significantly associated with the RNA expression of many other genes, with 3,127 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SFT2D2-associated genes across cancer lineages are DUX4, MIR6803, and BAG3. Each is linked with SFT2D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFT2D2-to-partner and partner-to-SFT2D2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFT2D2→partner) and Y-score (partner→SFT2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADDUX4 →+0.018+4.109<.001.00732
SKCMMIR6803 →+0.581+4.743<.001.00532
UCECBAG3 →+0.616+2.479<.001.00132
UCECCD8A →+0.672+1.857.005<.00132
UCECDONSON →+0.503+2.115<.001<.00132
UCECCHAF1B →+0.638+4.087<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,127 associations by consensus.

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