Across TCGA patient cohorts, SFT2D1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,004 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFT2D1-associated genes across cancer lineages are BRAT1, HMGCR, and GIPC1. Each is linked with SFT2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFT2D1-to-partner and partner-to-SFT2D1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFT2D1→partner) and Y-score (partner→SFT2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BRAT1 →	-0.609	-0.480	.003	<.001	3	2
LSCC	HMGCR →	-0.810	-0.335	<.001	.002	3	2
LSCC	GIPC1 →	-0.773	-0.289	<.001	.009	3	2
LSCC	FBXW9 →	-0.691	-0.354	<.001	.001	3	2
PDAC	ARL8B →	+0.443	+1.182	.003	.001	3	2
LSCC	FDPS →	-0.595	-0.439	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,004 associations by consensus.

Exploration

SFT2D1 survival (RNA) · tumor vs normal (RNA) · all SFT2D1 data types