Across TCGA patient cohorts, SFT2D1 mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SFT2D1-associated genes across cancer lineages are MIR6750, AQP7P2, and KRT18P14. Each is linked with SFT2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFT2D1-to-partner and partner-to-SFT2D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFT2D1→partner) and Y-score (partner→SFT2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6750 →	+0.594	+2.561	.002	.006	3	1
UCEC	AQP7P2 →	+0.162	+2.595	<.001	.005	3	1
UCEC	KRT18P14 →	+0.111	+2.826	.009	.005	3	1
UCEC	LONP1 →	+0.788	+3.201	.001	.009	3	1
UCEC	RNY1P1 →	+0.348	+4.113	<.001	.001	3	1
UCEC	RNU4-16P →	+0.301	+3.053	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Exploration

SFT2D1 survival (RNA) · tumor vs normal (RNA) · all SFT2D1 data types