Across TCGA cell cohorts, SFT2D1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SFT2D1-associated genes across cancer lineages are MMD2, UTF1, and PRR23C. Each is linked with SFT2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFT2D1-to-partner and partner-to-SFT2D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFT2D1→partner) and Y-score (partner→SFT2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	MMD2 →	+0.036	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	UTF1 →	+0.226	+5.357	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	PRR23C →	+0.006	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	USP17L22 →	+0.013	+5.357	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

SFT2D1 survival (RNA) · tumor vs normal (RNA) · all SFT2D1 data types