SFSWAP

Across TCGA cell cohorts, SFSWAP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,714 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SFSWAP-associated GO terms across cancer lineages are mRNA splice site recognition, Negative regulation of gene expression, epigenetic, and Promoter clearance during DNA-templated transcription. Each is linked with SFSWAP in more than 18 cancer types. Because this analysis shows association rather than direction, both SFSWAP-to-partner and partner-to-SFSWAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by SFSWAP-low versus SFSWAP-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFSWAP→partner) and Y-score (partner→SFSWAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	mRNA splice site recognition →	+0.183	+1.092	<.001	<.001	3	19
BONE	Negative regulation of gene expression, epigenetic →	+0.092	+1.184	<.001	<.001	3	17
OESOPHAGUS	Promoter clearance during DNA-templated transcription →	+0.139	+0.722	<.001	<.001	3	17
OESOPHAGUS	RNA polymerase II promoter clearance →	+0.139	+0.722	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	mRNA 5'-splice site recognition →	+0.146	+0.777	.004	.001	3	16
SOFT_TISSUE	mRNA cis splicing, via spliceosome →	+0.108	+0.891	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,714 associations by consensus.

mRNA splice site recognition by SFSWAP expression — OESOPHAGUS

Explore this box plot interactively →