SFRP5

Across TCGA patient cohorts, SFRP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,591 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SFRP5-associated proteins across cancer lineages are SLC25A5, HNRNPH2_S90, and HSPA12A. Each is linked with SFRP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SFRP5-to-partner and partner-to-SFRP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFRP5 versus SLC25A5 in OV, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SFRP5→partner) and Y-score (partner→SFRP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLC25A5 →	-0.627	-1.390	<.001	.001	3	3
LUAD	HNRNPH2_S90 →	-0.578	-1.041	<.001	.001	3	3
UCEC	HSPA12A →	+0.683	+0.819	<.001	<.001	3	3
CCRCC	ANKS1A_S663 →	+0.430	+0.371	.002	<.001	3	3
PDAC	ARHGAP44 →	+0.317	+1.431	.007	<.001	3	3
LUAD	G6PD →	-0.435	-0.852	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,591 associations by consensus.

SFRP5 vs SLC25A5 — OV

Explore this scatter interactively →