SFRP5

Across TCGA patient cohorts, SFRP5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,642 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFRP5-associated genes across cancer lineages are GP2, AMY2A, and TPM3P7. Each is linked with SFRP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFRP5-to-partner and partner-to-SFRP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFRP5 versus GP2 in PDAC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFRP5→partner) and Y-score (partner→SFRP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GP2 →	+4.775	+0.734	<.001	<.001	3	2
PDAC	AMY2A →	+3.871	+0.523	<.001	<.001	3	2
PDAC	TPM3P7 →	-0.503	-0.545	.001	.006	3	2
PDAC	SH3BP1 →	-0.519	-0.589	<.001	.004	3	1
PDAC	AP1B1 →	-0.283	-0.476	<.001	.002	3	1
PDAC	BMP7 →	-0.815	-0.470	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,642 associations by consensus.

SFRP5 vs GP2 — PDAC

Explore this scatter interactively →