SFRP5

Across TCGA cell cohorts, SFRP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 744 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SFRP5-associated GO terms across cancer lineages are Potassium ion transport, Potassium ion transmembrane transport, and Protein-DNA complex assembly. Each is linked with SFRP5 in more than 6 cancer types. Because this analysis shows association rather than direction, both SFRP5-to-partner and partner-to-SFRP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion transport grouped by SFRP5-low versus SFRP5-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFRP5→partner) and Y-score (partner→SFRP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Potassium ion transport →	-0.048	-0.177	.001	.005	2	6
SKIN	Potassium ion transmembrane transport →	-0.046	-0.174	.001	.006	2	6
BLOOD_Leukemia	Protein-DNA complex assembly →	+0.030	+0.696	.009	.008	2	6
BLOOD_Leukemia	Granzyme-mediated apoptotic signaling pathway →	+0.051	+0.833	.002	.004	1	7
LUNG_SCLC	Nucleoside triphosphate metabolic process →	+0.054	+1.144	.001	.007	3	5
OVARY	Protein-DNA complex organization →	+0.029	+0.270	.002	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 744 associations by consensus.

Potassium ion transport by SFRP5 expression — SKIN

Explore this box plot interactively →